Sonata Adomavičiūtė-Grabusovė
„Enhancing Vibrational Spectra of Biomolecules Using Non-standard Substrates and Materials“
This thesis shows the important role of SEVS techniques in advancing spectroscopy, despite the challenges that persist in optimizing these methods. As a response to many of the persistent challenges in advancing these techniques, this research focuses on several kinds of material manipulation to either improve the existing or identify novel substrates that could be utilized to boost the SEVS efficiency. This thesis employs both Surface Enhanced Infrared Absorption (SEIRA) and Surface Enhanced Raman Scattering (SERS) methods to enhance the detection of biologically relevant molecules. This includes improving the reproducibility and specificity of SERS substrates. This also includes expanding the applicability of the SEIRA technique for direct and remote sensing applications, in conjunction with enhancing optical fiber performance for in situ research.